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Written By
Rohit Singh -
Updated on
October 13th, 2025 -
Read Time
7 minutes
We all know that MS Outlook only supports MSG files. Email messages are stored within them, while attachments are usually saved in a proprietary format. Moreover, the inability to open an MSG file can stem from various factors. As a result, it ranges from software issues to file corruption. However, multiple users are looking for a solution to know how to resolve the “Cannot open MSG Files.” The pop-up says:
“Cannot start Microsoft Outlook. We can’t open ‘C:\Users\a40005772\Desktop\8D Training – 1st batch (268).msg’. It’s possible the file is already open, or you don’t have permission to open it.
To check your permissions, right-click the file folder, then click Properties.“
If you’re unable to open msg files in Outlook 2019 or 2021, there may be a few common reasons why. Now, let’s discuss these reasons below:
Here are some reasons to be unable to open MSG files in Outlook 365 error. Now, we will discuss how to resolve them.
Is your MSG file refusing to open in Outlook? The following section will discuss different ways to resolve the problem.
The following steps are as follows:
By following these straightforward steps, you can tweak your Outlook settings and potentially resolve the issue of MSG files not opening in Outlook.
If you’re having trouble opening MSG files, consider this simple solution: match the Outlook version. Here’s how:
Keep in mind that you can’t have two Outlook versions on one device. So, you have two options:
Option 1: Uninstall your current Outlook before installing the new version.
Option 2: Install Outlook on a different computer and try opening the MSG file there.
You might crack the code to open your MSG files by sticking to the correct Outlook version.
Opening MSG files shouldn’t be a headache. Follow these simple steps:
The above solution will help you to resolve the cannot open MSG file in Outlook 365 error. Moreover, we have other approaches for the same. You can also follow them.
If your MSG file still won’t open, don’t fret. Try re-enabling one add-in at a time to identify the cause.
If you’re having trouble opening MSG files in Outlook, your solution might be as simple as cleaning up temporary files.
C:\Users\%username%\AppData\Local\Microsoft\Windows\Temporary Internet Files\Content.Outlook
If that doesn’t work, try this:
OutlookSecureTempFolder
By clearing out these temporary files, you might give Outlook the boost it needs to handle MSG files smoothly.
If you’re having trouble opening Outlook email files (MSG files), how do you save them matters. Follow these simple steps:
Remember, the file format you use depends on your Outlook version. It’s a quick fix to ensure smooth handling of your MSG files.
If you’re facing errors opening MSG files, a simple solution might be updating your Windows operating system and Office application.
Update Windows:
Update Office:
If you have Microsoft Office from the Microsoft Store:
If you installed Office using a setup file:
If you’re facing MSG file errors in Outlook, it might be due to a corrupted Extend.dat file. Follow these simple steps to have Outlook recreate it:
By refreshing the Extend.dat file, you might solve those cannot open MSG files with Outlook 365 in no time. If the above solutions don’t work appropriately, opt for the MCD MSG Converter. It will help users to preview data files with a hierarchical folder. In fact, there is no data file limitation while using this software.
Related Post: Import Windows Live Mail to Outlook Email.
Encountering the “Cannot open MSG file” message indicates some problems, but don’t worry! Therefore, this blog post explains the potential causes and provides solutions. By following these steps, you can likely fix the issue and open your MSG files. Remember to stay patient and systematic. If the problem continues, it might be a good idea to ask for help from tech experts to make sure everything gets sorted out properly. Keep trying, and you’ll likely get it working.
Also Read: Import MSG to Thunderbird in Bulk.
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